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| Reactivity | Human Mouse |
| Tested applications | WB |
| Recommended Dilution | WB 1:1000 - 1:3000 |
| Calculated MW | 83kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human PDE4B |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
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