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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Calculated MW | 41kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human PEX14 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | NAPP2; PBD13A; Pex14p; dJ734G22.2; |
Western blot analysis of extracts of various cell lines, using PEX14 antibody.
Immunohistochemistry of paraffin-embedded human prostate cancer using PEX14 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using PEX14 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human liver injury using PEX14 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human lung cancer using PEX14 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of A549 cell using PEX14 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of A549 cell using PEX14 antibody. Blue: DAPI for nuclear staining.
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
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