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+1-888.733.6849
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| Reactivity | Human |
| Tested applications | WB FC |
| Recommended Dilution | WB 1:200 - 1:2000 FC 1:20 - 1:50 |
| Calculated MW | 12kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic peptide of human PHF5A |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | fj |
| Synonym | INI; Rds3; SF3B7; SAP14b; SF3b14b; bK223H9.2; |
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
N/A
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