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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Calculated MW | 39kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant Protein of human POLR1C |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | POLR1C ; RPA39; RPC40; AC40; POLR1E; RPA40 |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.Rush,J., Nat. Biotechnol. 23 (1), 94-101 (2005)Hirschler-Laszkiewicz,I., J. Biol. Chem. 278 (21), 18953-18959 (2003)Dammann,R., Biochim. Biophys. Acta 1396 (2), 153-157 (1998)Seither,P., Chromosoma 106 (4), 216-225 (1997)
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