For quotations, please use our online quotation form, and you may also contact us by
sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
Reactivity | Human Mouse |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Calculated MW | 53kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human PPAN |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | fj |
Synonym | SSF; SSF1; SSF2; BXDC3; SSF-1; |
Western blot analysis of extracts of various cell lines, using PPAN antibody.
Immunohistochemistry of paraffin-embedded human prostate using PPAN antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric using PPAN antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of A549 cell using PPAN antibody.
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
N/A