PPOX-Polyclonal Antibodies

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PPOX

Qty


Total
$220
Catalog #
A6397
Antibody Type
Polyclonal Antibody
Gene ID
5498
Swiss Prot
P50336
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Calculated MW50kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human PPOX
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymVP; PPO; V290M;
Images
  • A6397: image 1

    Immunofluorescence analysis of U2OS cell using PPOX antibody. Blue: DAPI for nuclear staining.

  • A6397: image 2

    Immunohistochemistry of paraffin-embedded human colon carcinoma using PPOX antibody at dilution of 1:100 (x40 lens).

  • A6397: image 3

    Immunohistochemistry of paraffin-embedded human liver injury using PPOX antibody at dilution of 1:100 (x40 lens).

  • A6397: image 4

    Immunohistochemistry of paraffin-embedded human lung cancer using PPOX antibody at dilution of 1:100 (x40 lens).

  • A6397: image 5

    Immunohistochemistry of paraffin-embedded human gastric using PPOX antibody at dilution of 1:100 (x40 lens).

Background

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Protocol

N/A

MSDS
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