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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Calculated MW | 50kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human PPOX |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | VP; PPO; V290M; |
Immunofluorescence analysis of U2OS cell using PPOX antibody. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human colon carcinoma using PPOX antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human liver injury using PPOX antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human lung cancer using PPOX antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human gastric using PPOX antibody at dilution of 1:100 (x40 lens).
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
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