PPP1CB-Polyclonal Antibodies

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PPP1CB

Qty


Total
$220
Catalog #
A1088
Antibody Type
Polyclonal Antibody
Gene ID
5500
Swiss Prot
P62140
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Calculated MW37kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human PPP1CB
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationq
SynonymPPP1CB;MGC3672;PP-1B;PPP1CD ;
Images
  • A1088: image 1

    Western blot analysis of extracts of various cell lines, using PPP1CB antibody.

  • A1088: image 2

    Immunohistochemistry of paraffin-embedded human esophageal cancer using PPP1CB antibody at dilution of 1:100 (400x lens).

  • A1088: image 3

    Immunofluorescence analysis of U2OS cell using PPP1CB antibody. Blue: DAPI for nuclear staining.

  • A1088: image 4

    Immunofluorescence analysis of U2OS cell using PPP1CB antibody. Blue: DAPI for nuclear staining.

Background

Protein phosphatase 1 (PP1) is the main eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular processes including protein-protein interactions, gene transcription, cell-cycle progression and apoptosis. It is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The catalytic subunit of PP1 (PP1c) can interact with amount of regulatory subunits in vivo that target it to particular subcellular locations and regulate its activity towards specific substrates. PPP1CB migrated as a 37kd protein on SDS page.

Protocol

N/A

MSDS
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