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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Calculated MW | 38kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human PPP1R8 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | ARD1; ARD-1; NIPP1; NIPP-1; PRO2047; |
Western blot analysis of extracts of various cell lines, using PPP1R8 antibody.
Immunohistochemistry of paraffin-embedded Human adenomyosis using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human gastric cancer using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human mammary cancer using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse brain using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse liver using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Rat brain using PPP1R8 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Rat stomach using PPP1R8 antibody at dilution of 1:100 (x400 lens).
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
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