|Reactivity||Human Mouse Rat|
|Tested applications||WB IHC IP|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:100
IP 1:20 - 1:50|
|Observed MW||Refer to Figures|
|Immunogen||Recombinant protein of human PPP3R1|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||ALNB1; CNB; CNB1|
Western blot analysis of extracts of various cells, using PPP3R1 antibody.
Immunohistochemistry of paraffin-embedded human prostate using PPP3R1 antibody at dilution of 1:100 (x40 lens).
Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.
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