PSMA4-Polyclonal Antibodies

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PSMA4

Qty


Total
$220
Catalog #
A2511
Antibody Type
Polyclonal Antibody
Gene ID
5685
Swiss Prot
P25789
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Calculated MW29kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human PSMA4
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymHC9; PSC9; HsT17706;
Images
  • A2511: image 1

    Western blot analysis of extracts of various cell lines, using PSMA4 antibody.

  • A2511: image 2

    Immunohistochemistry of paraffin-embedded human colon using PSMA4 antibody at dilution of 1:100 (x40 lens).

  • A2511: image 3

    Immunofluorescence analysis of U2OS cell using PSMA4 antibody. Blue: DAPI for nuclear staining.

  • A2511: image 4

    Immunofluorescence analysis of U2OS cell using PSMA4 antibody. Blue: DAPI for nuclear staining.

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Protocol

N/A

MSDS
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