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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:200 - 1:1000 IHC 1:20 - 1:200 |
Calculated MW | 48kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human PSTPIP1 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S; |
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
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