Phospho-EGFR-Y845-Monoclonal Antibodies

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Phospho-EGFR-Y845

Qty


Total
$300
Catalog #
AP0023
Antibody Type
Polyclonal Antibody
Gene ID
1956
Swiss Prot
P00533
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW134kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding Y845 of human EGFR
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationo
SynonymERBB; HER1; mENA; ERBB1; PIG61
Images
  • AP0023: image 1

    Western blot analysis of extracts of A431 cell line, using Phospho-EGFR-Y845 antibody.

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Protocol

N/A

MSDS
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