Phospho-NFKBIE-S22-Tag and Loading control Antibodies

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Phospho-NFKBIE-S22

Qty


Total
$300
Catalog #
AP0212
Antibody Type
Polyclonal Antibody
Gene ID
4794
Swiss Prot
O00221
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW40kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding S22 of human NFKBIE
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationkp
SynonymIKBE;
Images
  • AP0212: image 1

    Western blot analysis of extracts from 293 cells, using Phospho-NFKBIE-S22 antibody.

  • AP0212: image 2

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-NFKBIE-S22 antibody.

Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Protocol

N/A

MSDS
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