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sales@neoscientific.com
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+1-617.299.7367 (Int’l)
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| Reactivity | Human |
| Tested applications | WB |
| Recommended Dilution | WB 1:500 - 1:2000 |
| Calculated MW | 63kDa |
| Observed MW | Refer to figures |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S241 of human PDK1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | PDK1; PDPK2; PDPK2P; PRO0461; |
Phosphoinositide-dependent kinase 1 (PDPK1, PDK1) is a serine/threonine protein kinase integral to thefunction of the PI 3-K/Akt signaling pathway. PDK1 and mTORC2 both phosphorylate and activate PKB/Akt, ensuring a cellular response to stimuli such as growth factors and insulin signaling. Akt is the maineffector of PDK1.
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