|Recommended Dilution||WB 1:500 - 1:2000|
|Observed MW||Refer to figures|
|Immunogen||A phospho specific peptide corresponding to residues surrounding S241 of human PDK1|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||PDK1; PDPK2; PDPK2P; PRO0461;|
Phosphoinositide-dependent kinase 1 (PDPK1, PDK1) is a serine/threonine protein kinase integral to thefunction of the PI 3-K/Akt signaling pathway. PDK1 and mTORC2 both phosphorylate and activate PKB/Akt, ensuring a cellular response to stimuli such as growth factors and insulin signaling. Akt is the maineffector of PDK1.
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