QDPR-Polyclonal Antibodies

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QDPR

Qty


Total
$220
Catalog #
A3150
Antibody Type
Polyclonal Antibody
Gene ID
5860
Swiss Prot
P09417
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:1000 IHC 1:50 - 1:100
Calculated MW26kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human QDPR
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymDHPR; FLJ42391; PKU2; SDR33C1;
Images
  • A3150: image 1

    Western blot analysis of extracts of mouse liver tissue, using QDPR antibody.

Background

Dihydropteridine reductase (QDPR), also named as DHPR and HDHPR, is an essential enzyme in the hydroxylating system of the aromatic amino acids, since it catalyses the regeneration of tetrahydrobiopterin (BH4), the natural cofactor of phenylalanine, tyrosine, and tryptophan hydroxylases, from the quininoid-dihydrobiopterin produced in these coupled reactions(PMID:8326489). The QDPR protein is active as a dimer, with a subunit Mr of 26 kDa(PMID:7627180). This protein belongs to the short-chain dehydrogenases/reductases (SDR) family. Defects in QDPR are the cause of BH4-deficient hyperphenylalaninemia type C (HPABH4C)(PMID:11153907). This antibody is specific to QDPR.

Protocol

N/A

MSDS
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