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Reactivity | Human Mouse Rat |
Tested applications | WB FC |
Recommended Dilution | WB 1:500 - 1:2000 FC 1:50 - 1:100 |
Calculated MW | 130kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human RAD21 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21; |
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
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