RAD21-Polyclonal Antibodies

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RAD21

Qty


Total
$380
Catalog #
A5274
Antibody Type
Polyclonal Antibody
Gene ID
5885
Swiss Prot
O60216
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB FC
Recommended DilutionWB 1:500 - 1:2000 FC 1:50 - 1:100
Calculated MW130kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human RAD21
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymHR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21;
Images
  • A5274: image 1

    Western blot analysis of extracts of various cell lines, using RAD21 antibody.

Background

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Protocol

N/A

MSDS
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