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+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-617.299.7367 (Int’l)
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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Calculated MW | 42kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human RAD51C |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | FANCO; R51H3; BROVCA3; RAD51L2; |
Western blot analysis of extracts of various cells, using RAD51C antibody.
Immunohistochemistry of paraffin-embedded human prostate using RAD51C antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human gastric using RAD51C antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse stomach using RAD51C antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of U20S cell using RAD51C antibody.
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
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