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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50 |
| Calculated MW | 55kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human RBPJ |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | t |
| Synonym | SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1; |
Western blot analysis of extracts of mouse lung, using RBPJ antibody.
Immunohistochemistry of paraffin-embedded Human gastric using RBPJ antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded Human gastric cancer using RBPJ antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of MCF-7 cell using RBPJ antibody. Blue: DAPI for nuclear staining.
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
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