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| Reactivity | Human |
| Tested applications | WB IF |
| Recommended Dilution | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Calculated MW | 122kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human REST |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | XBR; NRSF; |
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described
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