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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Calculated MW | 61kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human RIPK2 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | bp |
| Synonym | CCK; RICK; RIP2; CARD3; GIG30; CARDIAK; |
Western blot analysis of extracts of various cell lines, using RIPK2 antibody.
Immunohistochemistry of paraffin-embedded rat kidney using RIPK2 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human liver injury using RIPK2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cell using RIPK2 antibody. Blue: DAPI for nuclear staining.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
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