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| Reactivity | Human Mouse |
| Tested applications | WB IP |
| Recommended Dilution | WB 1:200 - 1:2000 IP 1:20 - 1:50 |
| Calculated MW | 57kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human RIPK3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | bp |
| Synonym | RIPK3;RIP3 ; |
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
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