RPS6KA1-Polyclonal Antibodies

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RPS6KA1

Qty


Total
$380
Catalog #
A0135
Antibody Type
Polyclonal Antibody
Gene ID
6195
Swiss Prot
Q15418
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC ICC IP FC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100 ICC 1:50 - 1:200 IP 1:20 - 1:50 FC 1:20 - 1:50
Calculated MW83kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human RPS6KA1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationfpq
SynonymHU-1;MAPKAPK1A;RSK;RSK1;Ribosomal protein S6 kinase alpha-1 antibody; Ribosomal S6 kinase 1 antibody;
Images
  • A0135: image 1

    Western blot analysis of extracts of MCF7 cell line, using RPS6KA1 antibody.

Background

RSK 1 (p90-RSK 1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes RSK 1, RSK 2 and RSK 3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2. p90-RSK 1 is activated by MAPK in vitro and in vivo via phosphorylation. Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

Protocol

N/A

MSDS
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