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Reactivity | Human Mouse |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Calculated MW | 90kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic Peptide of human RPS6KA3 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CLS;HU-3;ISPK-1;MAPKAPK1B;MRX19;RSK;RSK2;S6K-alpha3;p90-RSK2;pp90RSK2;Ribosomal protein S6 kinase alpha-3 antibody;pp90RSK2 antibody; |
RSK2 is a member of the family of 90-kDa ribosomal S6 kinases. These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters. RSK2 phosphorylates a wide range of substrates, including ribosomal protein S6, and plays a significant role in mediating extracellular signal-related kinase (ERK) signal transduction. Mutations in RSK2 have been found to be associated with Coffin-Lowry syndrome.
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