|Tested applications||WB IHC|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:200|
|Observed MW||Refer to Figures|
|Immunogen||A synthetic Peptide of human RPS6KA3|
|Storage Buffer||Store at 4℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||CLS;HU-3;ISPK-1;MAPKAPK1B;MRX19;RSK;RSK2;S6K-alpha3;p90-RSK2;pp90RSK2;Ribosomal protein S6 kinase alpha-3 antibody;pp90RSK2 antibody;|
RSK2 is a member of the family of 90-kDa ribosomal S6 kinases. These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters. RSK2 phosphorylates a wide range of substrates, including ribosomal protein S6, and plays a significant role in mediating extracellular signal-related kinase (ERK) signal transduction. Mutations in RSK2 have been found to be associated with Coffin-Lowry syndrome.
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