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Reactivity | Human Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:100 - 1:500 |
Calculated MW | 35kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human SFRP1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | FRP; FRP1; FrzA; FRP-1; SARP2; |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
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