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+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| Calculated MW | 25kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human SIGMAR1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | SRBP; ALS16; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R; hSigmaR1; |
Western blot analysis of extracts of various cells, using SIGMAR1 antibody.
Immunohistochemistry of paraffin-embedded mouse kidney using SIGMAR1 antibody.
Immunohistochemistry of paraffin-embedded human stomach using SIGMAR1 antibody.
Immunohistochemistry of paraffin-embedded mouse brain using SIGMAR1 antibody.
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
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