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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IP |
| Recommended Dilution | WB 1:500 - 1:2000 IP 1:20 - 1:100 |
| Calculated MW | 34kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant Protein of human SIRT5 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | f |
| Synonym | SIR2L5; |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
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