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Reactivity | Human Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:1000 - 1:2000 |
Calculated MW | 60kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human SLC22A12 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | RST; OAT4L; URAT1; |
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.
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