SNAPIN-Monoclonal Antibodies

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SNAPIN

Qty


Total
$220
Catalog #
A10294
Antibody Type
Polyclonal Antibody
Gene ID
23557
Swiss Prot
O95295
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB
Recommended DilutionWB 1:200 - 1:2000
Calculated MW15kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human SNAPIN
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymBLOS7; BORCS3; SNAPAP; BLOC1S7;
Images
  • A10294: image 1

    Western blot analysis of extract of various cells, using SNAPIN antibody.

Background

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Protocol

N/A

MSDS
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