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Reactivity | Human Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:1000 - 1:2000 |
Calculated MW | 88kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human SPG7 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CAR; PGN; CMAR; SPG5C; |
This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
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