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Reactivity | Human Mouse |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Calculated MW | 17kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human SRGN |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | PPG; PRG; PRG1; |
Western blot analysis of extracts of various cell lines, using SRGN antibody.
Immunohistochemistry of paraffin-embedded human liver injury using SRGN antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of HeLa cell using SRGN antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of A549 cell using SRGN antibody. Blue: DAPI for nuclear staining.
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
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