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Reactivity | Human |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:1000 IHC 1:100 - 1:200 |
Calculated MW | 47kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human SSB |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | j |
Synonym | La; LARP3 |
Western blot analysis of extracts of 293 cell line, using SSB antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using SSB antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate cancer using SSB antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using SSB antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using SSB antibody at dilution of 1:100 (40x lens).
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.
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