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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Calculated MW | 66kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human STXBP2 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | FHL5; UNC18B; Hunc18b; UNC18-2; pp10122; MUNC18-2; |
Western blot analysis of extracts of various cells, using STXBP2 antibody.
Immunohistochemistry of paraffin-embedded human prostate using STXBP2 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse stomach using STXBP2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of A549 cell using STXBP2 antibody. Blue: DAPI for nuclear staining.
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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