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Reactivity | Human Mouse Rat |
Tested applications | WB IP |
Recommended Dilution | WB 1:500 - 1:2000 IP 1:20 - 1:50 |
Calculated MW | 48kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human SUV39H1 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
N/A