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| Reactivity | Human Mouse Rat |
| Tested applications | WB IF |
| Recommended Dilution | WB 1:200 - 1:2000 IF 1:10 - 1:100 |
| Calculated MW | 58kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic Peptide of human TBX5 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | bk |
| Synonym | HOS; |
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
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