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Reactivity | Human Mouse Rat |
Tested applications | WB IP |
Recommended Dilution | WB 1:500 - 1:2000 IP 1:20 - 1:100 |
Calculated MW | 235kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human TET1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | f |
Synonym | LCX; CXXC6; bA119F7.1;TET1 |
d contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
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