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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Calculated MW | 87kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human TLK2 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | HsHPK; PKU-ALPHA; |
Western blot analysis of extracts of various cell lines, using TLK2 antibody.
Immunohistochemistry of paraffin-embedded human liver injury using TLK2 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human esophageal cancer using TLK2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of U2OS cell using TLK2 antibody. Blue: DAPI for nuclear staining.
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.
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