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+1-888.733.6849
+1-617.299.7367 (Int’l)
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 31kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human TNFAIP6 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | TSG6; TSG-6; |
Immunohistochemistry of paraffin-embedded human gastric using TNFAIP6 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded rat kidney using TNFAIP6 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse heart using TNFAIP6 antibody at dilution of 1:100 (x40 lens).
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
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