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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Calculated MW | 213kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human TP53BP1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | p202; 53BP1; |
Western blot analysis of extracts of A431 cell line, using TP53BP1 antibody.
Immunofluorescence analysis of U20S cell using TP53BP1 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of GFP-RNF168 trangenic U2OS cell using TP53BP1 antibody. Green：GFP-RNF168 fusion protein expression for DNA damage marker.Blue: DAPI for nuclear staining.RNF168(GFP) can be used to mark cells damaged by UV-A laser for they always gather around DNA damage region.
TP53BP1 (tumor protein p53 binding protein 1) is a protein-coding gene. Go annotations related to this gene include methylated histone residue binding and p53 binding.Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis.Enhances TP53-mediated transcriptional activation.
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