TP63-Monoclonal Antibodies

our services
our products
Quotations & Ordering:

For quotations, please use our online quotation form, and you may also contact us by

[email protected]

Phone:

+1-888.733.6849
+1-617.299.7367 (Int’l)
+44-203.695.3777 (UK)

Fax:

+1-888.733.6849
+1-617.299.7367 (Int’l)

Our customer service representatives are available 24 hours, Monday through Friday to assist you.

TP63

Qty


Total
$220
Catalog #
A0089
Antibody Type
Monoclonal Antibody
Gene ID
8626
Swiss Prot
Q9H3D4
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:1000
Calculated MW77kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human TP63
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationbk
SynonymTP63;AIS;B(p51A);B(p51B);EEC3;KET;LMS;NBP;OFC8;RHS;SHFM4;TP53CP;TP53L;TP73L;p40;p51;p53CP;p63;p73H;p73L
Background

The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). In addition to p53, mammalian cells contain two p53 family members, TP63 and p73, which are similar to p53 in both structure and function (2). While TP63 can induce p53-responsive genes and apoptosis, mutation of TP63 rarely results in tumors (2). Amplification of the TP63 gene is frequently observed in squamous cell carcinomas of the lung, head and neck (2,3). The TP63 gene contains an alternative transcription intiation site that yields a 40 kDa deltaNTP63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the alpha, beta and gamma isoforms (3,4).

Protocol

N/A

MSDS
Reviews
Neo Scientific welcomes feedback from its customers.

If you have used an our product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information.

If you have any additional inquiries please email technical services at [email protected].

Thank you for your support.

promotions

Image

Custom Monoclonal Antibody
MassAb Technologies
Image
Free Trial Custom Polyclonal Antibody
You will receive free purified antibodies for validation
Image
Custom Peptides Synthesis

Start from $40/each

new technologies

Image
Optimized for enhanced
expression levels
XPromoter 2.0
Image
E.coli/insect cells/293 & CHO

3 in 1 expression system
Image
MassAb Technologies

Cover All Epitopes