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| Reactivity | Human |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:500 |
| Calculated MW | 83kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human TRPV6 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | g |
| Synonym | TRPV6;ABP/ZF;CAT1;CATL;ECAC2;HSA277909;LP6728;ZFAB ; |
The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV6 belongs to the V type subfamily, and it facilitates calcium entry across the plasma membrane in pancreas, placenta, and to a lesser extent stomach and kidney tissue. Furthermore, prostate cancer cells overexpress TRPV6, while benign prostate tissues do not express the protein, implying a role for TRPV6 in malignant growth.
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