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Reactivity | Human Mouse |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
Calculated MW | 15kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human TSHB |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | TSH-B; TSH-BETA; |
Immunohistochemistry of paraffin-embedded human prostate using TSHB antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using TSHB antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cell using TSHB antibody. Blue: DAPI for nuclear staining.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
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