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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IP |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:20 - 1:200 IP 1:20 - 1:50 |
Calculated MW | 17kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human UBE2N |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13; |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
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