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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Calculated MW | 27kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human UBE2R2 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | UBC3B; CDC34B; E2-CDC34B; |
Western blot analysis of extracts of various cell lines, using UBE2R2 antibody.
Immunohistochemistry of paraffin-embedded mouse cancer using UBE2R2 antibody at dilution of 1:100 (x400 lens).
Immunofluorescence analysis of A549 cell using UBE2R2 antibody.
Immunofluorescence analysis of A549 cell using UBE2R2 antibody.
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
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