XRCC1-Monoclonal Antibodies

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XRCC1

Qty


Total
$300
Catalog #
A0443
Antibody Type
Monoclonal Antibody
Gene ID
7515
Swiss Prot
P18887
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW85kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human XRCC1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentratione
SynonymXRCC1;RCC;DNA repair protein XRCC1;X-ray repair cross-complementing protein 1;
Images
  • A0443: image 1

    Western blot analysis of extracts of various cells, using XRCC1 antibody.

Background

The X-ray repair cross complementing protein 1 (XRCC1) is a DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents (1). XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins (2). At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK (3), DNA ligase III (4,5), poly (ADP-ribose) polymerase (6), and PCNA (7). Mutations and polymorphisms in the XRCC1 gene serve as diagnostic markers and are associated with elevated risk of various forms of cancers (8).

Protocol

N/A

MSDS
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