|Tested applications||WB IHC FC|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC1:20 - 1:50|
|Observed MW||Refer to Figures|
|Immunogen||A synthetic peptide of human YWHAZ|
|Storage Buffer||Store at 4℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||YWHAD; KCIP-1; 14-3-3-zeta;|
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
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