ANXA2 Human-Annexin

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ANXA2 Human

Qty


Total
$65
Catalog #
PRPS-784
Size
Description
ANXA2 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 376 amino acids (1-339a.a.) and having a molecular mass of 42.8 kDa. ANXA2 is fused to a 37 amino acid His-Tag at N-Terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionANXA2 is part of the annexin family and is involved in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein functions as an autocrine factor which increases osteoclast formation and bone resorption. ANXA2 is associated with sickle cell osteonecrosis. Reduced ANXA2 expression is associated with osteosarcoma metastases. ANXA2 is part of the putative cell surface vitamin D binding protein binding site complex and functions to mediate the chemotactic cofactor effect. ANXA2 is involved in dysferlin deficiency and in muscular dystrophies. Human colon adenocarcinoma cell differentiation is related with an up-regulation of ANXA2.
SynonymsANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV, ANXA2, Annexin A2, Annexin-2, Annexin II, Lipocortin II, Calpactin-1 heavy chain, Calpactin I heavy chain, Chromobindin-8, p36, Protein I, Placental anticoagulant protein IV.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationANXA2 solution containing 20mM Tris pH-8, 0.1M NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSHMST
VHEILCKLSL
EGDHSTPPSA
YGSVKAYTNF
DAERDALNIE
TAIKTKGVDE
VTIVNILTNR
SNAQRQDIAF
AYQRRTKKEL
ASALKSALSG
HLETVILGLL
KTPAQYDASE
LKASMKGLGT
DEDSLIEIIC
SRTNQELQEI
NRVYKEMYKT
DLEKDIISDT
SGDFRKLMVA
LAKGRRAEDG
SVIDYELIDQ
DA
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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