B2M Human, His-Beta 2 Microglobulin

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B2M Human, His

Qty


Total
$65
Catalog #
PRPS-866
Size
Description
B2M Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids (1-119 a.a.) and having a molecular mass of 14 kDa. The B2M is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionB2M is a part of the MHC class I family that participates in the presentation of peptide antigens to the immune system. B2M is localized on the surface of numerous cells and abundant on the surface of white blood cells. High production or destruction of these cells causes B2M levels in the blood to raise. This increase is observed in people with cancers involving white blood cells, but it is mainly significant in people newly diagnosed with multiple myeloma. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin''s lymphoma, and multiple myeloma or kidney disease.
SynonymsBeta-2-microglobin, Beta chain of MHC class I molecules, B2M, Beta 2 Microglobulin.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationB2M Human solution containing 20mM Tris pH-8, 2mM DTT, 0.1M NaCl & 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MIQRTPKIQV
YSRHPAENGK
SNFLNCYVSG
FHPSDIEVDL
LKNGERIEKV
EHSDLSFSKD
WSFYLLYYTE
FTPTEKDEYA
CRVNHVTLSQ
PKIVKWDRDM.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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