BCL2L10 Human-B Cell Lymphoma

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BCL2L10 Human

Qty


Total
$65
Catalog #
PRPS-1328
Size
Description
BCL2L10 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 195 amino acids (1-172 a.a.) and having a molecular mass of 21.8kDa.BCL2L10 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionBCL2 Like 10 (BCL2L10) is a member of the BCL-2 protein family. BCL2 family members form hetero or homodimers and serve as anti or pro-apoptotic regulators which are involved in a wide variety of cellular activities. BCL2L10 includes the conserved BH4, BH1 and BH2 domains. BCL2L10 interacts with other members of BCL2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. BCL2L10 overexpression suppresses cell apoptosis possibly throµgh the prevention of cytochrome C release from the mitochondria, and consequently activating caspase-3 activation.
SynonymsBcl-2-like protein 10, Bcl2-L-10, Anti-apoptotic protein NrH, Apoptosis regulator Bcl-B, BCL2L10, BCLB, Boo, Diva, BCL-B.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationBCL2L10 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMVDQLRE
RTTMADPLRE
RTELLLADYL
GYCAREPGTP
EPAPSTPEAA
VLRSAAARLR
QIHRSFFSAY
LGYPGNRFEL
VALMADSVLS
DSPGPTWGRV
VTLVTFAGTL
LERGPLVTAR
WKKWGFQPRL
KEQEGDVARD
CQRLVALLSS
RLMGQHRAWL
QAQGGWDGFC
HFFRT.
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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