CA8 Human-Carbonic Anhydrase

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CA8 Human

Qty


Total
$65
Catalog #
ENPS-242
Size
Description
CA8 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 314 amino acids (1-290) and having a molecular mass of 35.5kDa.CA8 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionCA8 was first called CA-related protein since there is a sequence similarity to other identified carbonic anhydrase genes. Still, this protein has no carbonic anhydrase activity - the reversible hydration of carbon dioxide. CA8 still holds a carbonic anhydrase designation due to obvious sequence similarity to other members of the carbonic anhydrase gene family. Mutations in CA8 result in cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3).
SynonymsCarbonic anhydrase VIII, CALS, CARP, CA-VIII, CAMRQ3, CA-related protein, carbonate dehydratase, carbonic anhydrase-like sequence, carbonic anhydrase-related protein.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CA8 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMADLSF
IEDTVAFPEK
EEDEEEEEEG
VEWGYEEGVE
WGLVFPDANG
EYQSPINLNS
REARYDPSLL
DVRLSPNYVV
CRDCEVTNDG
HTIQVILKSK
SVLSGGPLPQ
GHEFELYEVR
FHWGRENQRG
SEHTVNFKAF
PMELHLIHWN
STLFGSIDEA
VGKPHGIAII
ALFVQIGKEH
VGLKAVTEIL
QDIQYKGKSK
TIPCFNPNTL
LP
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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