CD1B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 310 amino acids (18-303a.a.) and having a molecular mass of 34.2kDa.CD1B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
CD1B belongs to CD1 family of transmembrane glycoproteins, which are structurally associated with the MHC proteins and form heterodimers with the beta-2-microglobulin. CD1B includes one Ig-like domain. CD1B is an antigen-presenting protein which connects self and nonself lipid and glycolipid antigens and displays them to T-cell receptors on natural killer T-cells.
CD1B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.